The manuscript should be written in English in a clear, direct and active style. All pages must be numbered sequentially, facilitating in the reviewing and editing of the manuscript.
The journal accepts original research articles, review articles and letters written in English. Single topic/thematic issues may also be considered for publication.
MANUSCRIPT SECTIONS FOR PAPERS
Manuscripts submitted for research and review articles in the respective journal should be divided into the following sections
- Title Page
- Structured Abstract
- Text organization
- List of abbreviations (if any)
- Consent for Publication
- Availability of Data and Materials
- Conflict of interest
- Figures/illustrations (if any)
- Chemical structures (if any)
- Tables (if any)
- Supportive/Supplementary Material (if any)
The title should be precise and brief and must not be more than 120 characters. Authors should avoid the use of non standard abbreviations and question marks in titles. The title must be written in title case except for articles, conjunctions and prepositions.
As recommended by the Reporting guidelines information about the study should be a part of the title (particularly for randomized or clinical trials, systematic reviews and meta analyses).
Authors should also provide a short ‘running title’. Title, running title, by line correspondent footnote and key words should be written as presented in the original manuscript.
Title page should include paper title, author(s) full name and affiliation, corresponding author(s) names complete affiliation/address, along with phone, fax and email
The abstract of an article should be its clear, concise and accurate summary, having no more than 250 words, and including the explicit sub-headings (as in-line or run-in headings in bold). Use of abbreviations should be avoided and the references should not be cited in the abstract.
All the original research articles, systematic reviews and meta analyses must be accompanied with a structured abstract. Ideally, each abstract should include the following sub-headings, but these may vary according to requirements of the article.
The headings can vary, but must state the purpose of the study, details of the participants, measurements, methods, main findings and conclusion.
The clinical trial studies should have the registration number at the end of the study.
6 to 8 keywords must be provided. Choose important and relevant keywords that researchers in your field will be searching for so that your paper will appear in a database search. The keywords should be contained in the title and they should appear several times in the article. In biomedical fields, MeSH terms are a good ‘common vocabulary’ source to draw keywords from https://www.nlm.nih.gov/mesh/meshhome.html.
The main text should begin on a separate page and should be divided into title page, abstract and the main text. The text may be subdivided further according to the areas to be discussed, which should be followed by the List of Abbreviations (if any), Conflict of Interest, Acknowledgements and Reference sections. For Review Articles, the manuscript should be divided into title page, abstract and the main text. The text may be subdivided further according to the areas to be discussed, which should be followed by the Acknowledgements and Reference sections. The Review Article should mention any previous important recent and old reviews in the field and contain a comprehensive discussion starting with the general background of the field. It should then go on to discuss the salient features of recent developments. The authors should avoid presenting material which has already been published in a previous review. The authors are advised to present and discuss their observations in brief.
For Research Articles the manuscript should begin with the title page and abstract followed by the main text, which must be structured into separate sections as Introduction, Materials and Methods, Results, Discussion, Conclusion, Ethics Approval and Consent to Participate, Human and Animal Rights, Conflict of Interest, Acknowledgements and References.
All randomized clinical trials must include a flow diagram and authors should provide a completed randomized trial checklist (see CONSORT Flow Diagram and Checklist; www.consort-statement.org) and a trial protocol.
The manuscript style must be uniform throughout the text and 10 pt Times New Roman fonts should be used. The full term for an abbreviation should precede its first appearance in the text unless it is a standard unit of measurement. The reference numbers should be given in square brackets in the text. Italics should be used for Binomial names of organisms (Genus and Species), for emphasis and for unfamiliar words or phrases. Non-assimilated words from Latin or other languages should also be italicized e.g. per se, et al., etc.
Section headings should be numbered sequentially, left aligned and have the first letter capitalized, starting with the introduction. Sub-section headings however, should be in lower-case and italicized with their initials capitalized. They should be numbered as 1.1, 1.2, etc.
The Introduction section should include the background and aims of the research in a comprehensive manner.
MATERIALS AND METHODS:
This section provides details of the methodology used along with information on any previous efforts with corresponding references. Any details for further modifications and research should be included. Sufficient details should be provided to the reader about the original data source in order to enable the analysis, appropriateness and verification of the results reported in the study.
It is important for the Method Section should be sufficiently detailed in respect of the data presented, and the results produced from it. This section should include all the information and protocol gathered for the study at the time when it was being written. If the study is funded or financially supported by an organization to conduct the research, then it should be mentioned in the Method Section. Methods must be result-oriented. The statement regarding the approval by an independent local, regional or national review committee (e.g. name of ethic committee and institutional review board) should be part of the Methods Section.
Repeated information should not be reported in the text of an article. A calculation section must include experimental data, facts and practical development from a theoretical perspective.
The important and main findings of the study should come first in the Results Section. The tables, figures and references should be given in sequence to emphasize the important information or observations related to the research. The repetition of data in tables and figures should be avoided. Results should be precise.
This should explore the significance of the results of the work, present a reproducible procedure and emphasis the importance of the article in the light of recent developments in the field. Extensive citations and discussion of published literature should be avoided.
This section of research articles should discuss the implications of the findings in the context of existing research and highlight the study's limitations. The authors should justify the sample size according to the study purpose and methods.
The Results and Discussion may be presented together under one heading of “Results and Discussion”. Alternatively, they may be presented under two separate sections (“Results” Section and “Discussion” Sections). Short sub-headings may be added in each section if required.
A small paragraph summarizing the contents of the article, presenting the final outcome of the research or proposing further study on the subject, may be given at the end of the article under the Conclusion section.
The authors need to declare the funding sources of their manuscripts clearly by providing the name of the funding agency or financial support along with allotted grant/award number in round brackets (if applied), for instance, “This work was financially supported by [Name of the funding agency] (Grant number XXX).
Similarly, if a paper does not have any specific funding source, and is part of the employment of the authors, then the name of the employer will be required. Authors will have to clearly state that the funder was involved in writing, editing, approval, or decision to publish the article.
HUMAN AND ANIMAL RIGHTS:
All clinical investigations should be conducted according to the Declaration of Helsinki principles. For all manuscripts reporting data from studies involving human participants, formal review and approval by an appropriate institutional review board or ethics committee are required.
For research involving animals, the authors should indicate whether the procedures followed were in accordance with the standards set forth in the eighth edition of “Guide for the Care and Use of Laboratory Animals” ( grants.nih.gov/grants/olaw/guide-for-the-care-and-use-of-laboratory-animals_prepub.pdf published by the National Academy of Sciences, The National Academies Press, Washington, D.C.).
Research Involving Animals:
Research work on animals should be carried out in accordance with the NC3Rs ARRIVE Guidelines. For In Vivo Experiments, please visit https://www.nc3rs.org.uk/arrive-guidelines
Authors should clearly state the name of the approval committee, highlighting that legal and ethical approvals were obtained prior to initiation of the research work carried out on animals, and that the experiments were performed in accordance with the relevant guidelines and regulations stated below.
- US authors should cite compliance with the US National Research Council's "Guide for the Care and Use of Laboratory Animals"
- The US Public Health Service's "Policy on Humane Care and Use of Laboratory Animals" and "Guide for the Care and Use of Laboratory Animals"
- UK authors should conform to UK legislation under the Animals (Scientific Procedures) Act 1986 Amendment Regulations (SI 2012/3039).
- European authors outside the UK should conform to Directive 2010/63/EU.
- Research on animals should adhere to ethical guidelines of the International Council for Laboratory Animal Science (ICLAS) ethical guidelines .
- The manuscript should clearly include a declaration of compliance with the relevant guidelines (e.g. the revised Animals (Scientific Procedures) Act 1986 in the UK and Directive 2010/63/EU in Europe) and/or relevant permissions or licenses obtained by the IUCN Policy Statement on Research Involving Species at Risk of Extinction and the Convention on the Trade in Endangered Species of Wild Fauna and Flora.
Compliance with the guidelines of the International Committee of Medical Journal Editors www.icmje.org) is recommended, in accordance with the patient’s consent for research or participation in a study as per the applicable laws and regulations regarding the privacy and/or security of personal information, including, but not limited to, the Health Insurance Portability and Accountability Act of 1996 ("HIPAA") and other U.S. federal and state laws relating to confidentiality and security of personally distinguishable evidence, the General Data Protection Regulation (GDPR) (EU) 2016/679 and member state implementing legislation, Canada's Personal Information Protection and Electronic Documents Act, India's Information Technology Act and related Privacy Rules, (together "Data Protection and Privacy Laws").
It is the responsibility of the author to ensure that:
- Patients' names, initials, or hospital numbers are not mentioned anywhere in the manuscript (including figures).
- Authors are responsible for obtaining the patient consent-to-disclose forms for all recognizable patients in photographs, videos, or other information that may be published in the Journal, in derivative works, or on the journal’s web site and for providing the manuscript to the recognizable patient for review before submission.
- The consent-to-disclose form should indicate specific use (publication in the medical literature in print and online, with the understanding that patients and the public will have access) of the patient's information and any images in figures or videos, and must contain the patient's signature or that of a legal guardian along with a statement that the patient or legal guardian has been offered the opportunity to review the identifying materials and the accompanying manuscript.
- If the manuscript has an individuals’ data, such as personal details, audio-video material, etc., consent should be obtained from that individual. In case of children, consent should be obtained from the parent or the legal guardian.
- A specific declaration of such approval and consent-to-disclose form must be made in the copyright letter and in a stand-alone paragraph at the end of the article especially in the case of human studies where inclusion of a statement regarding obtaining the written informed consent from each subject or subject's guardian is a must. The original should be retained by the guarantor or the corresponding author. Editors may request to provide the original forms by fax or email.
- All such case reports require by a proper consent being obtained prior to publishing. Please refer COPE guidelines available at https://publicationethics.org/resources/guidelines/journals'-best-practices-ensuring-consent-publishing-medical-case-reports .
Editors may request that authors provide documentation of the formal review and recommendation from the institutional review board or ethics committee responsible for oversight of the study. The editors reserve the right to reject manuscripts that do not comply with the above-mentioned requirements. The author will be held responsible for false statements or failure to fulfill the above-mentioned requirements.
Anonymous images, that do not identify the individual directly or indirectly, such as through any identifying marks or text, do not require formal consent, for example, X-rays, ultrasound images, pathology slides or laparoscopic images.
In case consent is not obtained, concealing the identity through eye bars or blurring the face would not be acceptable.
Research Involving Plants
All experimental research on plants (either cultivated or wild), should comply with international guidelines. The manuscript should include a declaration of compliance of field studies with relevant guidelines and/or relevant permissions or licenses obtained by the IUCN Policy Statement on Research Involving Species at Risk of Extinction and the Convention on the Trade in Endangered Species of Wild Fauna and Flora.
RESEARCH CONDUCTED IN SPECIAL OR CRITICAL SITUATIONS
Bentham OPEN expects all contributors to respect values of justice, benevolence, and autonomy when conducting research. We understand that certain situations such as medical emergencies or humanitarian crises may differ from non-emergency scenarios. Bentham OPEN recommends that research efforts should not hurt human subjects/respondents or the researchers, and should be conducted with sufficient scientific rigor as permissible in these situations, respectively. Care should be taken to address potential problems faced by persons who may be victims of disasters or involved in a medical emergency. These are vulnerable individuals and their privacy and dignity should be respected. Researchers should make note of this in their research and identify potential issues in their work that may arise because of such situations. Research directed in emergency circumstances should be to the greatest advantage of survivors involved in the research and with the goal of minimizing any future casualties. For guidance, the essential requirements of research in emergency situation are the preservation of human life, wellbeing and security, along with the rights to protection, privacy and confidentiality of subjects.
Unethical behavior and misconduct may be pointed out by anyone to the Editor and Publisher with sufficient evidences. The Editor, in consultation with the Publisher, will initiate investigation against this Unethical misconduct, complete the procedure till an unbiased decision is reached, and maintain confidentiality throughout the process of the investigation. The Author should be given the opportunity to reply to all minor or major accusations.
In case of serious breaches, the employer may be informed where appropriate, by the Editor/Publisher, after reviewing all available information and evidences or after seeking help from experts in that field.
- Author(s) and Reviewers must be informed in case of misinterpretation or mishandling of International Acceptable Standards
- A strict notice should be sent to the author and reviewer to avoid future unethical misconduct
- An Editorial on the reported misconduct should be published or official notice of unethical behavior should be posted on the website
- Official letter about this misconduct should be issued to the Head of Departments, Funding Agencies of the accused author and the reviewer, as well as Abstracting & Indexing Agencies.
- Where required, retraction and withdrawal of publication may be undertaken from the Publisher’s journal in discussion with the Head of the Department of the author or reviewer, and other higher authorities should be informed
- The Publisher may impose restrictions for some period on future publications from the accused author in the journals
Greek Symbols and Special Characters
Greek symbols and special characters often undergo formatting changes and get corrupted or lost during preparation of manuscript for publication. To ensure that all special characters used are embedded in the text, these special characters should be inserted as a symbol but should not be a result of any format styling (Symbol font face) otherwise they will be lost during conversion to PDF/XML.
Authors are encouraged to consult reporting guidelines. These guidelines provide a set of recommendations comprising a list of items relevant to their specific research design. All kinds of measurements should be reported only in International System of Units (SI). Chemical equations, chemical names, mathematical usage, unit of measurements, chemical and physical quantity & units must conform to SI and Chemical Abstracts or IUPAC.
In case there is a need to present lengthy, but essential methodological details, use appendices, which can be a part of the article. An appendix must not exceed three pages (Times New Roman, 10 point fonts, 900 max. words per page).The information should be provided in a condensed form, ruling out the need of full sentences. A single appendix should be titled APPENDIX, while more than one can be titled APPENDIX A, APPENDIX B, and so on.
Supportive/Supplementary Material (if any)
We do encourage to append supportive material, for example a PowerPoint file containing a talk about the study, a PowerPoint file containing additional screenshots, a Word, RTF, or PDF document showing the original instrument(s) used, a video, or the original data (SAS/SPSS files, Excel files, Access Db files etc.) provided it is inevitable or endorsed by the journal's Editor.
Supportive/Supplementary material intended for publication must be numbered and referred to in the manuscript but should not be a part of the submitted paper. In-text citations as well as a section with the heading "Supportive/Supplementary Material" before the "References" section should be provided. Here, list all Supportive/Supplementary Material and include a brief caption line for each file describing its contents.
Any additional files will be linked into the final published article in the form supplied by the author, but will not be displayed within the paper. They will be made available in exactly the same form as originally provided only on our Web site. Please also make sure that each additional file is a single table, figure or movie (please do not upload linked worksheets or PDF files larger than one sheet). Supportive/ Supplementary material must be provided in a single zipped file not larger than 4 MB.
Authors must clearly indicate if these files are not for publication but meant for the reviewers'/editors' perusal only.
List of Abbreviations (if any)
If abbreviations are used in the text either they should be defined in the text where first used, or a list of abbreviations should be provided.