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REVIEW ARTICLE

SARS-CoV-2 and Therapeutic Approaches

The Open COVID Journal 23 June 2022 REVIEW ARTICLE DOI: 10.2174/26669587-v2-e2204260

Abstract

In 2019, the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2) was first reported in Wuhan, China, affecting the population all over the globe. This ongoing pandemic is creating major havoc and has already taken the lives of many people. It has become really difficult to control the spread of the virus because of its high rate of multiplication in the host and transmission. The virus spreads by the means of droplets or direct contact with the infected person, causing pneumonia-like symptoms, such as fever, dry cough, throat pain, and breathlessness. This review presents the indications, mechanism of action, administration, and adverse effects of some antiviral, antibiotic, and immunomodulatory drugs, that are currently employed in the treatment of SARS-CoV-2. It also presents the effects and benefits of drugs on an infected person, when co-administered together.

Keywords: SARS-CoV-2, Antiviral, Anti-inflammatory, Antibiotic, Antioxidant, Vitamins, Cytokine storm, RNA-dependent RNA polymerase.
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