Recent Trends of Therapeutic Strategies against COVID-19

Hai-Long Zhang1, *, Liya Ge2, Yong-Xia Li1, Ai-Feng Zhou1
1 Central International Intellectual Property (Baotou) Co., Ltd. Baotou, 014030, China
2 Residues and Resource Reclamation Centre (R3C), Nanyang Environment and Water Research Institute, Nanyang Technological University, 1 Cleantech Loop, Clean Tech One, 637141, Singapore

Article Metrics

CrossRef Citations:
Total Statistics:

Full-Text HTML Views: 629
Abstract HTML Views: 264
PDF Downloads: 212
ePub Downloads: 139
Total Views/Downloads: 1244
Unique Statistics:

Full-Text HTML Views: 326
Abstract HTML Views: 157
PDF Downloads: 144
ePub Downloads: 78
Total Views/Downloads: 705

Creative Commons License
© 2022 Zhang et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

* Address correspondence to this author at the Central International Intellectual Property (Baotou) Co., Ltd., Baotou, China; E-mail:



The coronavirus disease 2019 (COVID-19), caused by a virus named SARS-CoV-2, has spread rapidly around the world.


To better understand the recent development of therapeutic strategies against COVID-19 and the patent landscape, we analyze patent documents surrounding COVID-19.


The patent documents surrounding COVID-19 from 6 major countries, including China, the US, Russia, Korea, India, and Singapore, were analyzed by a comprehensive analysis. The patent documents surrounding COVID-19 were published from November 2019 to April 2021.


The analysis showed that China was the most prolific country in patents surrounding COVID-19, with over 300 published patent documents. A significant feature of therapeutic strategies against COVID-19 was the contribution of traditional Chinese medicines in China. Our study showed the number of patents in the therapeutic area was about half in all patent applications, which indicated that therapeutic approaches, detecting, and protecting approaches were the same in importance against COVID-19.


The main therapeutic strategies against COVID-19 include traditional Chinese medicines, chemical drugs, and vaccines. An effective and fast approach against COVID-19 is to use vaccines or traditional Chinese Medicines. The present study showed the development of a therapeutic strategy surrounding COVID-19 based on patent insight for the first time and provided new insight into therapeutic strategy against COVID-19.

Keywords: COVID-19, Vaccine, Patent, Chemical drugs, Traditional chinese medicines, SARS-CoV-2.